
Lower extremity lesions in a female with Graves’ disease
Presenter: Cherise Khani, DO
Dermatology Program: St. Barnabas Hospital
CHIEF COMPLAINT: Swelling of bilateral lower extremities x 2 years and “raised circles on right shin and toes” x 9 months
CLINICAL HISTORY: A 44 year-old female presented with swelling of her bilateral lower extremities x 2 years, and “raised circles on right shin and toes” x 9 months. Lesions of the right lower extremity were associated only with mild intermittent pruritus. The patient denied pain, numbness, or paresthesias of affected area. She was diagnosed with Graves’ disease in 2009 and successfully treated with radioactive iodine. Resultant hypothyroidism has been well controlled with levothyroxine, without recurrence of symptoms. The patient had a recent surgical excision of masses on right and left great toes, as well as degenerated sesamoid bone of the right foot. The surgical pathology demonstrated benign fibroconnective tissue, showing a myxoid-mucoid background.