Large, Indurated, and Painful Plaque on the Forehead

Presenter:  Francisca Valenzuela, MD, Thomas L Davis, MD, Michael Hohnadel, DO

Dermatology Program: South Texas Dermatology Residency, HCA Healthcare Corpus Christi Medical Center – Bay Area Program

Program Director: Rick Lin, DO MPH FAOCD

Submitted on: June 12, 2024

 

CHIEF COMPLAINT: Large red protruding lesion on forehead

CLINICAL HISTORY: A 60-year-old female with no past medical history presented to the clinic with a large red lesion on her forehead and frontal scalp. The patient stated that it began as a small nodule approximately six months prior to her visit and had grown quickly, causing discomfort. She reported no history of head and neck surgeries or procedures. Notably, she had been seeing an oncologist for a couple of months due to anemia of unknown origin, and the oncology team referred her to dermatology for further evaluation of the large plaque.

PHYSICAL EXAM:
On physical examination, the patient had an erythematous, ulcerated, and indurated plaque with an overlying crust that had spread centrifugally across the entirety of her frontal scalp. No satellite lesions were noted.

 

 

LABORATORY TESTS: N/A

DERMATOHISTOPATHOLOGY:

Histopathologic studies showed the dermis containing irregular vascular spaces lined by atypical endothelial cells that protruded into their lumina.

 

DIFFERENTIAL DIAGNOSIS:

    1.   Angiosarcoma
    2.   Sarcoidosis
    3.   Squamous Cell Carcinoma
    4.   Lymphoma
    5.   Tufted Angioma
    6.   Kaposi Sarcoma

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