Presenter: Joseph Del Priore, DO
Dermatology Program: Western University/ Pacific Hospital
Program Director: David C. Horowitz, DO FACD
Submitted on: January 21, 2011
CHIEF COMPLAINT: Bump on arm
CLINICAL HISTORY: A 19-year-old male presented with a pink, shiny 3 cm protuberant nodule on his right upper extremity that grew rapidly over 2 months. A previous treatment of tea tree oil was tried.
PHYSICAL EXAM:
Solitary 3.2cm well-circumscribed, shiny pink nodule on the right upper arm that is hard and slightly painful upon palpation.
LABORATORY TESTS: N/A
DERMATOHISTOPATHOLOGY:
Histopathological examination showed sections of nests of cells, some of which presented with a basaloid appearance with regular crowded oval nuclei. There were also associated ghost cells with residual eosinophilic cytoplasm and without preserved nuclei. Scattered chronic inflammatory cells along with multinucleated giant cells and a focus of calcification were present. No evidence of malignancy was identified.
DIFFERENTIAL DIAGNOSIS:
1. Dermatofibrosarcoma protuberans
2. Pilomatricoma / pilomatrical carcinoma
3. Melanoma
4. SCC
5. BCC