Hyperkeratotic plaques on the lower extremities

Presenter: Heather Orkwis, DO

Dermatology Program: St. Joseph Mercy Hospital

Program Director: Daniel Stewart, DO

Submitted on: December 17, 2011

 

CHIEF COMPLAINT:  >10 year history of dark, itchy spots on legs

CLINICAL HISTORY: A 44-year-old woman presented with a greater-than-10-year history of dark, itchy spots on legs. She complained of pruritic, progressively worsening dark spots on the bilateral anterior lower legs. She used a bleaching cream on the areas 8 years prior without improvement. The patient has insulin resistance, hypertension, and arthritis.

PHYSICAL EXAM:
There are hyperpigmented, keratotic plaques on the bilateral anterior lower extremities.

 

LABORATORY TESTS: N/A

DERMATOHISTOPATHOLOGY:
Punch biopsy showed a hyperkeratotic epidermis overlying papillary dermal deposits of homogenous material.

 

DIFFERENTIAL DIAGNOSIS:

1.   Acquired Ichthyosis
2.   Lichen Aureus
3.   Lichen Simplex Chronicus
4.   Keratosis Pilaris
5.   Scleroderma

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