Painful lower extremity nodules, pancreatitis, and polyarthritis
Presenter: Paul M. Graham
Dermatology Program: St. Joseph Mercy Dermatology
CHIEF COMPLAINT: Exquisitely painful nodules and marked edema of his bilateral lower legs
CLINICAL HISTORY: A 69-year-old Caucasian man presented with exquisitely painful nodules and marked edema of his bilateral lower legs. The nodules first appeared nine months ago and have shown a waxing and waning course. His past medical history includes chronic pancreatitis of unknown origin, hypertension, gastroesophageal reflux disease, inflammatory arthritis, and hypercholesterolemia. The patient reported experiencing painful skin nodules on his lower extremities for the past eight months, alongside joint pain and swelling in the metacarpophalangeal (MCP), metatarsophalangeal (MTP), and ankle joints. He had previously been treated with intralesional corticosteroid injections, which yielded only a marginal response. Additionally, he used high-potency topical corticosteroids and nonsteroidal anti-inflammatory drugs for symptomatic pain relief. Notably, the patient has a history of numerous hospital admissions for pancreatitis and is currently being managed by Rheumatology for his arthritic symptoms.